The fourth-largest city in California, San Francisco vacation rentals are a great way to explore this incredible metropolitan area! Known world-wide for steep hills, Alcatraz, and the Golden Gate Bridge, San Francisco is an inspiring, diverse and culturally significant community. Founded in the 19th century and prospering during the Gold Rush, San Francisco was completely destroyed in 1906 by an earthquake, but was quickly rebuilt and has stood strong ever since. If visiting, make sure to check out Chinatown, Haight-Ashbury, and the Transamerica Pyramid.